MDL 100907

CAS: 139290-65-6

Ref. 3D-FV28720

Información del producto

• Nombre: MDL 100907
• Sinónimos: (a-R)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanolM 100907Volinanserin, (+)-Mdl 100907, (+)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol, (2,3-Dimethoxyphenyl){1-[2-(4-Fluorophenyl)Ethyl]Piperidin-4-Yl}Methanol, (R)-(2,3-Dimethoxyphenyl)-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]methanol, (aR)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol, 4-Piperidinemethanol, 1-[2-(4-Fluorophenyl)Ethyl]-Alpha-(2,3-Dimethoxyphenyl)-, (Alphar), 4-Piperidinemethanol, α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-, (R)-, 4-Piperidinemethanol, α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-, (αR)-, M 100907, Mdl100907, R-Mdl 100907, Volinanserin

Descripción

Selective antagonist of the serotonin receptors 5-HT2A with subnanomolar affinity. The compound has clozapine-like anti-psychotic properties and more favourable CNS safety profile than traditional anti-psychotics. MDL 100907 has been used in studies on antisocial behaviour in mice and shown that the blockage of 5-HT2A receptors leads to decreased post-traumatic aggression and bradycardia.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 373.46 g/mol
• Fórmula: C₂₂H₂₈FNO₃
• Pureza: Min. 95%
• Color/Forma: White Solid
• InChI: InChI=1S/C22H28FNO3/c1-26-20-5-3-4-19(22(20)27-2)21(25)17-11-14-24(15-12-17)13-10-16-6-8-18(23)9-7-16/h3-9,17,21,25H,10-15H2,1-2H3/t21-/m1/s1
• Clave InChI: InChIKey=HXTGXYRHXAGCFP-OAQYLSRUSA-N
• SMILES: COc1cccc([C@H](O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC