Zofenoprilat

CAS: 75176-37-3

Ref. 3D-FZ41737

Información del producto

• Nombre: Zofenoprilat
• Sinónimos: (1(R*),2Alpha,4Alpha)-1-(3-Mercapto-2-Methyl-1-Oxopropyl)-4-(Phenylthio)-L-Proline, (2S,4S)-1-[(2R)-2-Methyl-3-Sulfanyl-Propanoyl]-4-Phenylsulfanyl-Pyrrolidine-2-Carboxylic Acid, (4S)-1-[(2S)-3-Mercapto-2-methyl-1-oxopropyl]-4-(phenylthio)-<span class="text-smallcaps">L</span>-proline, <span class="text-smallcaps">L</span>-Proline, 1-(3-mercapto-2-methyl-1-oxopropyl)-4-(phenylthio)-, [1(R*),2α,4α]-, <span class="text-smallcaps">L</span>-Proline, 1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]-4-(phenylthio)-, (4S)-, Sq 26333

Descripción

Zofenoprilat is a prodrug of enalaprilat, which is an inhibitor of angiotensin-converting enzyme (ACE). It has been shown to reduce the blood pressure in vivo and in humans. Inhibition of ACE leads to decreased levels of angiotensin II and aldosterone, which are hormones that constrict blood vessels. Zofenoprilat also inhibits the transcription-polymerase chain reaction (PCR) by binding to DNA-dependent RNA polymerase and preventing its activity. This drug may be used as an alternative to ACE inhibitors when they are contraindicated or ineffective. The inhibition of ACE by zofenoprilat also prevents the formation of angiotensin II, which is involved in the activation of pro-angiogenic processes.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 325.45 g/mol
• Fórmula: C₁₅H₁₉NO₃S₂
• Pureza: Min. 95%
• Color/Forma: Powder