Información del producto
Redd1 is a transcriptional regulator that functions as a negative regulator of inflammation. Redd1 induces the expression of IL-12 in human monocytes, which can lead to the suppression of inflammatory responses. Redd1 also inhibits the development of regulatory T cells and Th17 cells, which are important for maintaining immune tolerance. Redd1 is induced by microbial products and the pathogen Toxoplasma gondii, but it is overridden by IL-12 in the presence of this cytokine. The induction of Redd1 is mediated by IL-12 through activation of STAT3 transcription factor.
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Propiedades químicas
Consulta técnica sobre: 3D-GHA37335 Redd1 inducer
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