(2S)-1-(1-Oxo-2-propen-1-yl)-4-[5,6,7,8-tetrahydro-7-(3-hydroxy-1-naphthalenyl)-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]pyrido[3,4- d]pyrimidin-4-yl]-2-piperazineacetonitrile
CAS: 2206735-61-5
Ref. 3D-GND73561
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Información del producto
(2S)-1-(1-Oxo-2-propen-1,4-yl)-4-[5,6,7,8-tetrahydro-7-(3-hydroxy-1-naphthalenyl)-2-[(2S)-1-methylpyrrolidinium]methoxy]pyrido[3,4-d]pyrimidin-4-yl]-2-[(2S)-1-(N'-methylcarbamoyl)pyrrolidinium]acetonitrile (known as GTS 2422) is a potent and highly selective antagonist of the human 5HT receptor. It has been shown to inhibit the binding of serotonin to the 5HT receptor in rat brain synaptosomes with an IC50 value of 0.44 nM. GTS 2422 has also been shown to inhibit the binding of serotonin to the 5HT receptor in human platelets with an
Propiedades químicas
Consulta técnica sobre: 3D-GND73561 (2S)-1-(1-Oxo-2-propen-1-yl)-4-[5,6,7,8-tetrahydro-7-(3-hydroxy-1-naphthalenyl)-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]pyrido[3,4- d]pyrimidin-4-yl]-2-piperazineacetonitrile
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