Harmine

CAS: 442-51-3

Ref. 3D-H-1200

Información del producto

• Nombre: Harmine
• Sinónimos: 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole, 1-Methyl-7-methoxy-β-carboline, 7-Methoxy-1-methyl-9H-beta-carbolin, 7-Methoxy-1-methyl-9H-beta-carboline, 9H-Pyrido(3,4-b)indole, 7-methoxy-1-methyl-, Banisterin, Banisterine, Banisterine Monohydrate, Harmin, Leucoharmine, Telepathin, Telepathine, Yagein, Yageine
• CAS: 442-51-3

Descripción

Harmine is a molecule that interacts with DNA by binding to the minor groove, which is the non-helical area of DNA. Harmine has been shown to have cytotoxic properties in murine hepatoma cells, as well as anticancer activity in mouse tumor cells. Harmine also has antiviral and antimicrobial effects, and has been shown to inhibit the growth of human cancer cells. Harmine binds to Toll-like receptor 4 (TLR4), which is a pattern recognition receptor that plays an important role in innate immunity. Harmine inhibits TLR4 signaling, thereby inhibiting inflammatory responses such as acute toxicities. The molecular docking analysis of harmine shows that it has high affinity for polymerase chain reaction (PCR) enzymes and can be used for PCR inhibition studies. The analytical method for harmine was developed using a natural compound crystal structure as a model system.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 212.25 g/mol
• Fórmula: C₁₃H₁₂N₂O