ASN03576800
CAS: 957513-35-8
Ref. 3D-HNB51335
5mg | Descatalogado | ||
10mg | Descatalogado | ||
25mg | Descatalogado | ||
50mg | Descatalogado | ||
100mg | Descatalogado |
Información del producto
- 2-[[2-(1,3-Benzodioxol-5-ylamino)-2-oxoethyl]sulfinyl]acetic acid
- Acetic acid, 2-[[2-(1,3-benzodioxol-5-ylamino)-2-oxoethyl]sulfinyl]-
ASN03576800 is a molecule inhibitor of Ebola virus. It has shown potent antiviral activity against the Ebola virus in vitro, with a 50% inhibitory concentration (IC50) of 0.4 μM for the viral matrix protein. ASN03576800 blocks viral binding and entry into host cells, as well as inhibiting viral RNA synthesis. ASN03576800 also inhibits the expression of human cellular genes that are regulated by the transcription factor NF-κB, which is activated by pro-inflammatory cytokines and mediates pro-inflammatory and anti-apoptotic signals. This inhibition can be due to its ability to bind to the RNA component of these viruses, preventing them from binding to their target cells.