N-[4-Amido-3-(trifluoromethyl)phenyl-3-[(4-fluorophenyl)-(R,S)-sulphinyl]-(R,S)-2-hydroxy-2-methylpropanamide

CAS: 945419-64-7

Ref. 3D-IA58276

Información del producto

• Nombre: N-[4-Amido-3-(trifluoromethyl)phenyl-3-[(4-fluorophenyl)-(R,S)-sulphinyl]-(R,S)-2-hydroxy-2-methylpropanamide
• Sinónimos: 4-Amide-3-trifluoromethyl-N-(3-p-fluorophenylsulfinyl-(R,S)-2-hydroxy-2-methylpropionyl)anilineBicalutamide sulfoxideN-[4-Cyano-3- (trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfinyl]-2-hydroxy-2-methylpropanamideBicalutamide Impurity A

Descripción

N-[4-Amino-3-(trifluoromethyl)phenyl-3-[(4-fluorophenyl)-(R,S)-sulphinyl]- (R,S)-2-hydroxy-2-methylpropanamide is a sulfoxide that was designed to inhibit cancer cell proliferation. It has been shown to have anticancer activity in different models. The synthesis of this compound begins with the chlorination of 4-aminophenol, which produces 4-(chloromethyl)benzenesulfonyl chloride. This is then reacted with (R,S)-α-(4-Fluorophenyl)acetic acid and the resulting product is purified by column chromatography to give N-[4-(chloromethyl)phenyl]-3-[(4-fluorophenyl)(R,S)-sulphinyl]propaneamide. The final step in the synthesis is achieved by reacting the amide

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 414.37 g/mol
• Fórmula: C₁₈H₁₄F₄N₂O₃S
• Pureza: Min. 95%
• Color/Forma: White To Off-White Solid