13-O-Desmethyl tacrolimus

CAS: 139958-51-3

Ref. 3D-ID161984

Información del producto

• Nombre: 13-O-Desmethyl tacrolimus

Descripción

Tacrolimus is a macrolide immunosuppressant that is used to prevent organ rejection in transplant patients. It binds to the cytosolic protein, FKBP-12, which prevents calcineurin from dephosphorylating and activating nuclear factor of activated T cells (NFAT). Tacrolimus inhibits the production of IL-2 and other cytokines by T cells, suppressing proliferation. Tacrolimus has been shown to be bioequivalent when administered orally or intravenously. Bioavailability may be increased when taken with food.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 789.99 g/mol
• Fórmula: C₄₃H₆₇NO₁₂
• Pureza: 90%Min
• Color/Forma: Powder