Dansylcadaverine

CAS: 10121-91-2

Ref. 3D-KAA12191

Información del producto

• Nombre: Dansylcadaverine
• Sinónimos: 1-Naphthalenesulfonamide, N-(5-aminopentyl)-5-(dimethylamino)-, Monodansylcadaverine, N-(5-Aminopentyl)-5-(dimethylamino)-1-naphthalenesulfonamide

Descripción

Dansylcadaverine is a fluorescent dye that binds to basic proteins in the cell. It has been shown to induce apoptosis in 3t3-l1 preadipocytes and can be used as a marker for apoptotic cells or as a marker of autophagy. The fluorescence intensity of dansylcadaverine increases when it binds to basic proteins on the surface of human pathogens, such as the surface glycoprotein on HIV-1. This binding has been shown to lead to induction of autophagy in macrophages, which may help clear these pathogens from the body and prevent disease progression. Dansylcadaverine also has physiological effects on mammalian cells, including an effect on epidermal growth factor receptor, which can be used for studying receptor-ligand interactions.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 335.46 g/mol
• Fórmula: C₁₇H₂₅N₃O₂S
• Pureza: Min. 95%
• Color/Forma: Powder