Chloromethyl propyl carbonate
CAS: 35273-90-6
Ref. 3D-KBA27390
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Información del producto
Chloromethyl propyl carbonate is a pyrimidine compound that has been proposed as a potential cancer drug. It has shown high resistance to the enzymes fatty acid synthase and tenofovir and has shown antiviral properties against HIV, herpes simplex, and hepatitis B. Chloromethyl propyl carbonate inhibits the production of acyclic nucleoside phosphonates. It also inhibits fatty acid synthesis by binding to the enzyme acyl-CoA synthetase 2. Chloromethyl propyl carbonate binds to nitrogen atoms in the active site of the enzyme glutamine synthetase, thereby inhibiting its activity. The pharmacokinetic properties of chloromethyl propyl carbonate have been studied in rats and dogs; it is absorbed orally with rapid distribution into tissues, including fat, liver, kidney, lung, and brain. The drug is metabolized by carboxyesterases in the liver and excreted in urine
Propiedades químicas
Consulta técnica sobre: 3D-KBA27390 Chloromethyl propyl carbonate
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