PyBOP®

CAS: 128625-52-5

Ref. 3D-KPC-1068-PI

Información del producto

• Nombre: PyBOP&reg
• Sinónimos: (1-Hydroxy-1H-benzotriazolato-O)tri-1-pyrrolidinylphosphorus(1+) hexafluorophosphate(1-), 1-Benzotriazolyloxytripyrrolidinylphosphonium hexafluorophosphate, 1H-Benzotriazol-1-yloxytripyrrolidinophosphonium Hexafluorophosphate, 1H-Benzotriazole, 1-hydroxy-, phosphorus complex, Benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate, Benzotriazol-1-yloxytripyrrolidinophosphonium hexafluorophosphate, Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate, Phosphorus(1+), [1-(hydroxy-κO)-1H-benzotriazolato]tri-1-pyrrolidinyl-, (T-4)-, hexafluorophosphate(1-) (1:1), PyBOP, Pyrrolidine, phosphorus complex
• CAS: 128625-52-5

Descripción

PyBOP is an acyclic nucleoside phosphonate that is structurally similar to cyclic peptides and coumarin derivatives. It has been shown to be active against infectious diseases such as malaria and hepatitis C, as well as metabolic disorders such as obesity. PyBOP also has a number of physiological effects, including thermal expansion and immunomodulation. PyBOP binds to the 3'-hydroxyl group of RNA by hydrogen bonding interactions in vivo and inhibits rRNA synthesis, leading to the inhibition of protein synthesis. This drug also disrupts the disulfide bond between cysteine residues in proteins, which may lead to autoimmune diseases.

PyBOP is water-soluble and highly soluble in organic solvents, but not soluble in water or polar solvents such as DMSO or acetone.
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The thermal expansion coefficient for PyBOP is about 10^6 K^-1mol^

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 520.39 g/mol
• Fórmula: C₁₈H₂₈N₆OPPF₆
• Pureza: Min. 95%