Información del producto
ML 077 is a pyridazine that is being studied as a potential treatment for cancer. It has been shown to disrupt the assembly of the nuclear pore complex, which is responsible for regulating the passage of molecules between the nucleus and cytoplasm. In cells, ML 077 binds to nucleoporin-Nup98, preventing its attachment to other proteins in the complex. This disruption prevents the formation of a functional nuclear pore complex and inhibits cell growth.
Propiedades químicas
Consulta técnica sobre: 3D-KVB30461 ML 077
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