5-Bromomethyl-3-methyl-isoxazole+
CAS: 36958-61-9
Ref. 3D-LBA95861
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Información del producto
5-Bromomethyl-3-methyl-isoxazole+ is an inhibitor of thymidylate synthase (TS). TS catalyzes the conversion of deoxyuridine monophosphate to dUMP and dihydrofolate. 5-Bromomethyl-3-methyl-isoxazole+ shows significant inhibition of cell proliferation, with a potency similar to that of the lead compound Lsd1. In addition, this inhibitor has good oral bioavailability in humans and does not show any cytotoxicity towards human cells. The IC50 for 5-bromomethyl-3-methyl-isoxazole+ is less than 1 nM.
Propiedades químicas
Consulta técnica sobre: 3D-LBA95861 5-Bromomethyl-3-methyl-isoxazole+
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