VU 0364770
CAS: 61350-00-3
Ref. 3D-LCA35000
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| 25mg | A consultar | |
| 50mg | A consultar | |
| 100mg | A consultar | |
| 250mg | A consultar |
Información del producto
VU 0364770 is an allosteric modulator of the N-methyl-D-aspartate (NMDA) receptor. It is a competitive antagonist of the glutamate binding site on the NMDA receptor and inhibits the activity of this receptor. VU 0364770 has been shown to reduce symptoms in patients with mild to moderate Alzheimer's Disease, and also has anti-inflammatory properties. Analysis by X-ray diffraction data has revealed that VU 0364770 binds to a hydrophobic pocket in the NMDA receptor and blocks the hydrogen bonds between residues on the allosteric site. VU 0364770 also has neuroprotective effects by reducing neuronal death due to nitric oxide production and oxidative stress.
Propiedades químicas
Consulta técnica sobre: 3D-LCA35000 VU 0364770
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