Información del producto
- (1R)-1-[[(1-Methylethyl)amino]methyl]-2-(1-naphthalenyloxy)ethyl β-D-glucopyranosiduronic acid
- (+)-Propranolol glucuronide
- β-D-Glucopyranosiduronic acid, (1R)-1-[[(1-methylethyl)amino]methyl]-2-(1-naphthalenyloxy)ethyl
- β-D-Glucopyranosiduronic acid, 1-[[(1-methylethyl)amino]methyl]-2-(1-naphthalenyloxy)ethyl, (R)-
Propranolol is a racemic mixture of two optical isomers, which are (R)-propranolol and (S)-propranolol. The (-) form of propranolol metabolizes to the (+) form, and vice versa. The (+) form is more potent than the (-) form as an anti-hypertensive agent. It has been shown that the metabolism of propranolol in microsomes from rat liver differs from that in human liver microsomes. Both forms of propranolol can be metabolized by cytochrome P450 enzymes, but the (-) form can also be metabolized by esterases and glucuronidases.
Propiedades químicas
Consulta técnica sobre: 3D-MP35493 (R)-Propranolol glucuronide
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