Saridegib
CAS: 1037210-93-7
Ref. 3D-MRB21093
5mg | A consultar | ||
10mg | A consultar | ||
25mg | A consultar | ||
50mg | A consultar |
Información del producto
Saridegib is a novel, potent and selective inhibitor of the protein kinase C-epsilon (PKC-epsilon). Saridegib has been shown to inhibit the activity of PKC-epsilon in vitro. PKC-epsilon is expressed in high levels in metastatic pancreatic cancer cells, which are resistant to conventional chemotherapy. Saridegib inhibits cancer cell growth and survival by blocking the production of inflammatory cytokines such as interleukin-1beta (IL-1β) and tumor necrosis factor alpha (TNFα). Saridegib also inhibits human skin cancer cells by inhibiting the production of IL-8 and TNFα. This drug has also been shown to be effective against inflammatory diseases such as rheumatoid arthritis and psoriasis.
Propiedades químicas
Consulta técnica sobre: 3D-MRB21093 Saridegib
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