O6-Benzyl-N2,3-etheno guanosine

CAS: 108060-84-0

Ref. 3D-NB16629

Información del producto

• Nombre: O6-Benzyl-N2,3-etheno guanosine
• Sinónimos: 4-(Phenylmethoxy)-1-b-D-ribofuranosyl-1H-imidazo[2,1-b]purine

Descripción

O6-Benzyl-N2,3-etheno guanosine is a phosphoramidite that can be used in the synthesis of DNA. It is a novel nucleoside analog with antiviral and anticancer properties. O6-Benzyl-N2,3-etheno guanosine has been shown to increase the antitumor activity of cisplatin in vitro and in vivo, as well as its ability to inhibit human immunodeficiency virus type 1 (HIV-1) replication. This compound also inhibits the replication of herpes simplex virus type 2 (HSV-2) without affecting the expression of cellular proteins. O6-Benzylguanosine is synthesized by reacting N2,3-ethenoguanosine with benzaldehyde in dichloromethane under microwave irradiation.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 397.38 g/mol
• Fórmula: C₁₉H₁₉N₅O₅
• Pureza: Min. 95%