5-Chlorouridine
CAS: 2880-89-9
Ref. 3D-NC02866
| 1g | A consultar | ||
| 2g | A consultar | ||
| 5g | A consultar | ||
| 10g | A consultar | ||
| 500mg | A consultar |
Información del producto
- 5-Chloro-D-uridine
- 5-Chloro-1-[(3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
- 5-chloro-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione
5-Chlorouridine is a nucleoside with hypochlorous acid. It has been shown to inhibit the growth of tumor cells in tissue culture and to have an inhibitory effect on cervical cancer, which may be due to its ability to inhibit cellular metabolism and DNA synthesis. 5-Chlorouridine inhibits the uptake of uridine by blocking the conversion of uridine into cytosine, thereby preventing DNA synthesis. This prodrug also prevents radiation from inducing mutations in DNA. The molecular modeling study shows that 5-chlorouridine forms hydrogen bonds with hydroxyl groups in RNA, which may be important for its anti-cancer activity.
Propiedades químicas
Consulta técnica sobre: 3D-NC02866 5-Chlorouridine
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