5'-O-DMT-2'-O-methyluridine

CAS: 103285-22-9

Ref. 3D-ND03001

Información del producto

• Nombre: 5'-O-DMT-2'-O-methyluridine
• Sinónimos: 5'-O-DMT-2'-O-methyl-D-uridine, Dmt-2'-O-Methyluridine, 5'-O-(Dimethoxytrityl)-2'-O-Methyluridine, 2'-O-Methyl-5'-O-DMT-Uridine, 5'-O-DMT-2'-O-Methyl-Uridine

Descripción

5'-O-DMT-2'-O-methyluridine (5'-OMeT) is a modified nucleoside that is used in biological research. It is an oligonucleotide analogue with the same sequence as thymine, but with a 2'-O-methyl group at the 5' position and a 5' O-dimethoxytrityl group. The stability of 5'-OMeT has been studied by thermal denaturation studies and found to be more stable than other analogues such as 6-azacytidine, 6-azauridine, and 6-azathymidine. This may be due to its increased resistance to endonucleolytic cleavage. 5'-OMeT has not shown any significant biological activity in vivo or in vitro.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 560.61 g/mol
• Fórmula: C₃₁H₃₂N₂O₈
• Pureza: Min. 95%
• Color/Forma: White Powder