2',3'-Dideoxy-3'-fluorouridine

CAS: 41107-56-6

Ref. 3D-ND04228

Información del producto

• Nombre: 2',3'-Dideoxy-3'-fluorouridine
• Sinónimos: 1-(2,3-Dideoxy-3-fluoro-b-D-ribofuranosyl)uracil2',3'-Dideoxy-3'-fluoro-D-uridine3'-Fluoro-2',3'-dideoxyuridine, 1-(2,3-Dideoxy-3-fluoro-β-<span class="text-smallcaps">D</span>-ribofuranosyl)uracil, 1-(2,3-dideoxy-3-fluoropentofuranosyl)pyrimidine-2,4(1H,3H)-dione, 2′,3′-Dideoxy-3′-fluorouridine, 3'-Fluoro-2',3'-dideoxyuridine, 3′-Fluoro-2′,3′-dideoxyuridine, Fddurd, Uridine, 2',3'-dideoxy-3'-fluoro-, Uridine, 2′,3′-dideoxy-3′-fluoro-, 1-(2,3-Dideoxy-3-fluoro-β-D-ribofuranosyl)uracil

Descripción

2',3'-Dideoxy-3'-fluorouridine (ddFU) is a nucleoside analog that inhibits the human immunodeficiency virus-1 (HIV-1). It is transported into cells and inhibits HIV-1 replication by inhibiting the reverse transcriptase enzyme. This agent has been shown to be effective against HIV-1 in vivo, with an inhibitory dose of 1 mg/kg and an effective dose of 2.5 mg/kg. ddFU also has a significant inhibitory effect on human mitochondrial DNA polymerase γ and can be used for the treatment of hepatitis B and C.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 230.2 g/mol
• Fórmula: C₉H₁₁FN₂O₄
• Pureza: Min. 95%
• Color/Forma: White Powder