2'-Deoxy-8-(9H-fluoren-2-ylamino)-guanosine

CAS: 73051-69-1

Ref. 3D-ND10433

Información del producto

• Nombre: 2'-Deoxy-8-(9H-fluoren-2-ylamino)-guanosine
• Sinónimos: Guanosine, 2'-deoxy-8-(9H-fluoren-2-ylamino)-, N-(2′-Deoxyguanosin-8-yl)-2-aminofluorene, N-(Deoxyguanosin-8-yl)-2-aminofluorene, N-(Deoxyguanosine-C8-yl)-2-aminofluorene

Descripción

2'-Deoxy-8-(9H-fluoren-2-ylamino)-guanosine (FdA) is a synthetic nucleoside that was designed for use as a dietary supplement to inhibit carcinogenesis. It is an analog of guanosine and is phosphorylated by cellular kinases to form 2'-deoxy-8-(9H-fluoren-2-ylamino)-inosine monophosphate. FdA inhibits the process of DNA replication in mammalian cells, which may be due to its ability to bind single stranded DNA. This drug has been shown to reduce the mutation frequency and increase the life span of mice with bladder cancer.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 446.46 g/mol
• Fórmula: C₂₃H₂₂N₆O₄
• Pureza: Min. 95%