N-(2'-Deoxy- 2', 2'- difluorocytidine 5'-P- phenyl phosphate) L- alanine benzyl ester

CAS: 840506-29-8

Ref. 3D-ND158438

Información del producto

• Nombre: N-(2'-Deoxy- 2', 2'- difluorocytidine 5'-P- phenyl phosphate) L- alanine benzyl ester
• Sinónimos: N- (2'- Deoxy- 2', 2'- difluoro- P- phenyl- 5'- cytidylyl) -L- alanine phenylmethyl esterAcelarin
• CAS: 840506-29-8

Descripción

N-(2'-Deoxy-2',2'-difluorocytidine-5'-P-phenyl-phosphate) L-alanine benzyl ester (DFCP) is an anti-cancer compound that was developed to target leukemic stem cells, which are resistant to traditional chemotherapy drugs. DFCP inhibits the formation of uridine nucleotides, which are required for DNA synthesis and cell proliferation. DFCP has been shown to have a high therapeutic index in animal studies, with low toxicity and low side effects. In vitro experiments have demonstrated that this drug can inhibit the growth of solid tumours and plasma concentration-time curve data in mice show that it is able to reduce metastatic pancreatic cancer.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 580.47 g/mol
• Fórmula: C₂₅H₂₇F₂N₄O₈P
• Pureza: Min. 98 Area-%
• Color/Forma: Powder