3-Deazauridine

CAS: 23205-42-7

Ref. 3D-ND16524

Información del producto

• Nombre: 3-Deazauridine
• Sinónimos: 4-Hydroxy-1-β-D-ribofuranosyl-2(1H)-pyridinone1-β-D-Ribofuranosyl-4-hydroxy-2-pyridone
• Marca: Biosynth
• Descripción: 3-Deazauridine is a uridine analog that inhibits the synthesis of DNA, RNA, and protein. It has been shown to inhibit the activity of 3-deazauridine synthetase in HL-60 cells. 3-Deazauridine also has significant cytotoxicity against colorectal adenocarcinoma cells and synergistic effects when used with other chemotherapeutic agents. The mechanism of action of 3-deazauridine is similar to that of other enzyme inhibitors, such as glycosidic bond formation or competitive inhibition. The sample preparation for this drug is complicated by its insolubility in water.

Propiedades químicas

• Peso molecular: 243.21 g/mol
• Fórmula: C₁₀H₁₃NO₆
• Pureza: Min. 97 Area-%
• Color/Forma: White Powder