5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine

CAS: 163759-50-0

Ref. 3D-ND36302

Información del producto

• Nombre: 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine
• Sinónimos: 5'-O-DMT-2'-O-MOE-5-methyluridine
• Marca: Biosynth
• Descripción: 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine is a novel, synthetic nucleoside with antiviral and antitumor activity. It is an analogue of 5'-O-DMT-2'-O-(2-methoxyethyl)uridine, which has been shown to be active against herpes simplex virus type 1 (HSV1) in vitro. The phosphoramidites of 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine are modified at the 2' position with a methyl group and at the 5' position with a methoxyethyl group. These modifications make it more resistant to degradation by intracellular enzymes. The anticancer activity of 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine was demonstrated in preclinical studies using human tumor cell lines.

Propiedades químicas

• Peso molecular: 618.67 g/mol
• Fórmula: C₃₄H₃₈N₂O₉
• Pureza: Min. 95%
• Color/Forma: Off-White Powder