2',3'-Dideoxy-2',3'-didehydro-2'-fluorocytidine

CAS: 122757-53-3

Ref. 3D-ND90458

Información del producto

• Nombre: 2',3'-Dideoxy-2',3'-didehydro-2'-fluorocytidine
• Sinónimos: 2,3-Ddfc, Cytidine, 2',3'-didehydro-2',3'-dideoxy-2'-fluoro-, 4-amino-1-[(2R,5S)-3-fluoro-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidin-2(1H)-one

Descripción

2',3'-Dideoxy-2',3'-didehydro-2'-fluorocytidine (ddC) is a nucleoside with antiviral activity. The mechanism of action is not well understood, but ddC has been shown to inhibit the proliferation of human immunodeficiency virus (HIV). It is also active against isolates of herpes simplex virus and vesicular stomatitis virus. The elimination half-life of ddC in humans is about 8 hours. In humans, this drug is eliminated by methylation and glucuronidation reactions. The pharmacokinetics of ddC have been studied in animals, including rats and rabbits, with preliminary indications that the elimination half-life may be longer than in humans.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 227.19 g/mol
• Fórmula: C₉H₁₀FN₃O₃
• Pureza: Min. 95%