2'-Deoxy-5-ethynyluridine

CAS: 61135-33-9

Ref. 3D-NE08701

Información del producto

• Nombre: 2'-Deoxy-5-ethynyluridine
• Sinónimos: 2'-Deoxy-5-ethynyluridine5-Ethynyl-2'-deoxyuridine5-EdU, 2,4(1H,3H)-pyrimidinedione, 1-(2-deoxypentofuranosyl)-5-ethynyl-, 5-Ethynyl-2'-Deoxyuridine, Uridine, 2'-Deoxy-5-Ethynyl-
• CAS: 61135-33-9

Descripción

2'-Deoxy-5-ethynyluridine (5-EdU) is a modified thymidine analogue containing a terminal alkyne group, which is used for nucleotide labelling. 5-Edu is easily taken up by cells and incorporated by metabolic activation during DNA synthesis. By adding an azide conjugated to a fluorophore or a biotin moiety, a click reaction occurs from the labelled nucleotide linked by a triazole group. 5-Edu are employed in cell proliferation assays, to study DNA and RNA localisation, structure and dynamics, in the synthesis of aptamers with the click-SELEX method, and in other applications such as the preparation of oligonucleotide microarrays and nanoelectronic devices.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 252.23 g/mol
• Fórmula: C₁₁H₁₂N₂O₅
• Pureza: Min. 98 Area-%
• Color/Forma: Powder