8-Hydroxyadenosine

CAS: 29851-57-8

Ref. 3D-NH08494

Información del producto

• Nombre: 8-Hydroxyadenosine
• Sinónimos: 8-Hydroxy-D-adenosine, Adenosine, 8-Oxo-, 6-amino-9-pentofuranosyl-7,9-dihydro-8H-purin-8-one

Descripción

8-Hydroxyadenosine (8-OHdG) is a purine nucleoside that is formed as a result of oxidative DNA damage. It is not an essential metabolite because it can be synthesized de novo. 8-OHdG has been shown to have potent anti-tumor activity in vitro and in vivo, which may be due to its ability to inhibit DNA replication. The biological effects of 8-OHdG are attributed to its ability to form hydrogen bonds with guanine residues in the double helix, and electrochemical detectors have been developed for its detection.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 283.25 g/mol
• Fórmula: C₁₀H₁₃N₅O₅
• Pureza: Min. 98 Area-%
• Color/Forma: Powder