9-(b-D-Ribofuranosyl)purine

CAS: 550-33-4

Ref. 3D-NR05251

Información del producto

• Nombre: 9-(b-D-Ribofuranosyl)purine
• Sinónimos: Nebularine, 9-(alpha-D-xylofuranosyl)-9H-purinato(2-), 9-(beta-D-ribofuranosyl)-9H-purine, 9-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-9H-purine, 9-β-<span class="text-smallcaps">D</span>-Ribofuranosylpurine, 9-β-<span class="text-smallcaps">D</span>-Ribosyl-9H-purine, 9H-Purine, 9-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, Desaminoadenosine, Isopurine, ribosyl-, NSC 65423, Purine Riboside, Purine-9-β-<span class="text-smallcaps">D</span>-ribofuranoside, Purinosine, Ribosylpurine

Descripción

9-(b-D-Ribofuranosyl)purine (9-BRP) is a purine nucleoside that is used in the synthesis of dyes. It has been shown to be an effective inhibitor of the enzyme phosphodiesterase 3B, which breaks down cyclic adenosine monophosphate (cAMP), and therefore can prevent kidney fibrosis. 9-BRP has also been shown to inhibit the synthesis of collagen by binding to cAMP. In addition, 9-BRP binds to DNA and forms hydrogen bonds with nitrogen atoms on the phosphate groups in DNA. This interaction prevents the formation of hydrogen bonds between water molecules in water vapor and phosphate groups, thus slowing down their rate of dissociation from each other. 9-BRP also has a high affinity for Toll-like receptor 4 (TLR4), which is involved in the inflammatory response, making it an ideal therapeutic candidate for treating inflammation and renal fibrosis.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 252.23 g/mol
• Fórmula: C₁₀H₁₂N₄O₄
• Pureza: Min. 97 Area-%
• Color/Forma: Powder