GM3NeuGc-Ganglioside
Ref. 3D-OG158639
1mg | A consultar | ||
2mg | A consultar |
Información del producto
Ganglioside GM3NeuGc (sodium salt) has a core disaccharide structure (Galβ1,4Glc) with N-glycolyl sialic acid linked α2,3 to the galactose residue, and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GM3(NeuGc) ganglioside is of interest due to its restrictive expression in normal human tissues, according to immunohistochemical studies, using either polyclonal or monoclonal antibodies. However, both immunohistochemical and biochemical methods have strongly suggested its over-expression in human breast tumours (Oliva, 2006). It is seen as a possible tumor-associated carbohydrate antigen for cancer immunotherapy (Changping, 2019).
Propiedades químicas
Consulta técnica sobre: 3D-OG158639 GM3NeuGc-Ganglioside
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