Información del producto
- Gb3α-D-Gal-(1→4)-β-D-Gal-(1→4)-β-D-Glc-1→O-ceramideCeramide trihexosides
- 71965-57-6
- Cd 77
- Ceramide trihexoside
- Ceramide, 1-O-(O-α-<span class="text-smallcaps">D</smallcap>-galactopyranosyl-(1→4)-O-β-<smallcap>D</smallcap>-galactopyranosyl-(1→4)-β-<smallcap>D</span>-glucopyranosyl)-
- Fabry glycolipid
- Ganglioside G<sub>L3</sub>
- Ganglioside Gb<sub>3</sub>
- Gb<sub>3</sub>
- Gb<sub>3</sub>Cer
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- Globo-N-triaosylceramide
- Globotriglycosylceramide
- Globotriosylceramide
- Shiga toxin receptor
- Trihexosylceramide
It is one of the few clusters of differentiation that is not a protein and structurally contains a galactose moiety linked α to lactosylceramide. Defects in the enzyme α-galactosidase lead to the buildup of globotriaosylceramide, causing Fabry's disease. The pharmaceutical drug migalastat enhances the function of α-galactosidase and is used to treat Fabry's. Globotriaosylceramide is also one of the targets of Shiga toxin, which is responsible for pathogenicity of enterohemorrhagic E. coli.
Propiedades químicas
Consulta técnica sobre: 3D-OG45939 Globotriaosylceramide
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