Endothelin-3 (Human)

CAS: 117399-93-6

Ref. 3D-PED-4199-V

Información del producto

• Nombre: Endothelin-3 (Human)
• Sinónimos: Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp
• Marca: Biosynth
• Descripción: Endothelin-3 (ET-3) is a protein that belongs to the large family of endothelin peptides which activate the G-protein coupled receptors ETA and ETB. However ET-3 has lower affinity for the ETA receptors compared to Endothelin-1 (ET-1) and Endothelin-2 (ET-2), whereas all three endothelins have similar affinity for ETB receptors. As ETB receptors make up around 90% of the endothelin receptors found in the cerebral cortex in humans, ET-3 can be nicknamed the ‘brain endothelin’. Also through ET-3’s activation of ETB receptors, ET-3 is involved in the development of the enteric nervous system which controls within the gut, blood flow, secretion and intestinal motility. This product has disulfide bonds between Cys1-Cys and Cys3-Cys11, is sourced from Porcine, Rat and Rabbit and is available as a 0.5mg vial

Propiedades químicas

• Peso molecular: 2,643 g/mol
• Fórmula: C₁₂₁H₁₆₈N₂₆O₃₃S₄
• Pureza: Min. 95%