Imperatoxin A

CAS: 172451-37-5

Ref. 3D-PIM-4343-S

Información del producto

• Nombre: Imperatoxin A
• Sinónimos: IpTXa Gly-Asp-Cys-Leu-Pro-His-Leu-Lys-Arg-Cys-Lys-Ala-Asp-Asn-Asp-Cys-C ys-Gly-Lys-Lys-Cys-Lys-Arg-Arg-Gly-Thr-Asn-Ala-Glu-Lys-Arg-Cys-Arg, Iptxa, Imperatoxin A, Pandinus Imperator, H-Gly-Asp-Cys-Leu-Pro-His-Leu-Lys-Arg-Cys-Lys-Ala-Asp-Asn-Asp-Cys-Cys-Gly-Lys-Lys-Cys-Lys-Arg-Arg-Gly-Thr-Asn-Ala-Glu-Lys-Arg-Cys-Arg-Oh, H-Gly-Asp-Cys-Leu-Pro-His-Leu-Lys-Arg-Cys-Lys-Ala-Asp-Asn-Asp-Cys-Cys-Gly-Lys-Lys-Cys-Lys-Arg-Arg-Gly-Thr-Asn-Ala-Glu-Lys-Arg-Cys-Arg-Oh (Disulfide Bonds Undetermined), Gly-Asp-Cys-Leu-Pro-His-Leu-Lys-Arg-Cys-Lys-Ala-Asp-Asn-Asp-Cys-Cys-Gly-Lys-Lys-Cys-Lys-Arg-Arg-Gly-Thr-Asn-Ala-Glu-Lys-Arg-Cys-Arg, Ptx(A), H-Gly-Asp-Cys-Leu-Pro-His-Leu-Lys-Arg-Cys-Lys-Ala-Asp-Asn-Asp-Cys-Cys-Gly-Lys-Lys-Cys-Lys-Arg-Arg-Gly-Thr-Asn-Ala-Glu-Lys-Arg-Cys-Arg-OH (Disulfide bridges are not determined)

Descripción

A synthetic scorpion toxin consisting of disulfide bonds between Cys3-Cys17, Cys10-Cys21, and Cys16-Cys32. It can be used as an activator of Ca2+ Release Channels/Ryanodine Receptors. It is important to understand the functions of Ryanodine receptors as they mediate Ca2+ release from intracellular reticular stores and this is imperative for signalling processes, namely muscle excitation-contraction coupling. If skeletal and cardiac Ryanodine receptor genes are mutated diseases such as congenital myopathy and metabolic disorders occur. Therefore Imperatoxin A is useful in investigating these diseases. This product is avaiable as a 0.1mg vial.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 3,758.4 g/mol
• Fórmula: C₁₄₈H₂₅₄N₅₈O₄₅S₆
• Pureza: Min. 95%