Información del producto
Nombre:FR167344
Marca:Biosynth
Descripción:FR167344 is a b2 receptor antagonist that inhibits the binding of the ligands bradykinin and thromboxane A2 to their receptors. It has been shown to be effective in the treatment of inflammatory diseases such as pancreatitis, and also for reducing leukotriene synthesis. The pharmacokinetics of FR167344 have been studied in rats, mice, and healthy volunteers. It is absorbed from the gastrointestinal tract and eliminated by liver metabolism. The drug is eliminated mainly through renal excretion of unchanged drug, with less than 1% metabolized by the liver.FR167344 has been shown to inhibit binding of bradykinin to its receptor in cell membrane preparations from human epidermoid carcinoma (A431) cells and lung fibroblasts, with a maximal response at concentrations between 0.1-10 µM.
Aviso:Nuestros productos están destinados únicamente para uso en laboratorio. Para cualquier otro uso, por favor contáctenos.
Propiedades químicas
Peso molecular:673.4 g/mol
Fórmula:C30H28BrCl2N5O4
Pureza:Min. 95%
Consulta técnica sobre: FR167344
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