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8-(6-Methoxypyridin-3-yl)-3-methyl-1-(4-piperazin-1-yl)-3-(trifluoromethyl)phenyl-1H-imidazol[4,5-c]quinolin-2(3H)-one
CAS: 915020-55-2
Ref. 3D-QLB02055
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Información del producto
The chemical compound 8-(6-Methoxypyridin-3-yl)-3-methyl-1-(4-piperazin-1-yl)-3-(trifluoromethyl)phenyl-1H-imidazol[4,5-c]quinolin-2(3H)-one is an imidazoquinoline that inhibits the phosphatidylinositol 3 kinase (PI3K)/mammalian target of rapamycin (mTOR) signaling pathway. This inhibition prevents the activation of certain proteins, including protein kinase B (PKB), which regulates cell growth and proliferation. This inhibition leads to a decrease in the production of phosphatidylinositol 3,4,5 trisphosphate (PIP3). PIP3 binds to the pleckstrin homology domain of Akt and promotes its activity. Hence, this inhibition leads to decreased Akt activity
Propiedades químicas
Consulta técnica sobre: 3D-QLB02055 8-(6-Methoxypyridin-3-yl)-3-methyl-1-(4-piperazin-1-yl)-3-(trifluoromethyl)phenyl-1H-imidazol[4,5-c]quinolin-2(3H)-one
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