2-Chloro-N-methyl-5-(trifluoromethyl)pyrimidin-4-amine

CAS: 515824-43-8

Ref. 3D-QVA82443

Información del producto

• Nombre: 2-Chloro-N-methyl-5-(trifluoromethyl)pyrimidin-4-amine

Descripción

2-Chloro-N-methyl-5-(trifluoromethyl)pyrimidin-4-amine is a novel chemical entity that inhibits the enzyme GNE. It has been shown to have a high metabolic stability and to be selective for GNE over other enzymes. 2-Chloro-N-methyl-5-(trifluoromethyl)pyrimidin-4-amine is being investigated as a therapeutic agent for treating diseases such as hepatic encephalopathy and nonalcoholic steatohepatitis. This molecule has been shown to inhibit the production of proinflammatory cytokines in hepatocytes, which may be due to its ability to inhibit protein synthesis by inhibiting the activity of GNE.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 211.57 g/mol
• Fórmula: C₆H₅ClF₃N₃
• Pureza: Min. 95%