Methylenebis-phosphonic acid tetramethyl ester

CAS: 16001-93-7

Ref. 3D-RAA00193

Información del producto

• Nombre: Methylenebis-phosphonic acid tetramethyl ester
• Sinónimos: Methylenediphosphonic acid tetramethyl ester, Tetramethyl Methanediylbis(Phosphonate)

Descripción

Methylenebisphosphonic acid is a phosphonic acid with an inhibitory effect on enzymes. It has been shown to have strong inhibitory properties against gram-negative bacteria and inhibits the growth of Mycobacterium tuberculosis. Methylenebisphosphonic acid also inhibits the production of cytokines, such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β), by inflammatory cells, which may contribute to its anti-inflammatory properties. Methylenebisphosphonic acid also blocks apoptotic cell death by inhibiting the activation of caspase 3, an enzyme that cleaves other proteins involved in apoptosis. Methylenebisphosphonic acid binds to Ca2+ response proteins and blocks their ability to regulate cellular processes. This prevents the release of cytochrome C from mitochondria, which initiates a cascade of reactions leading to cell death.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 232.11 g/mol
• Fórmula: C₅H₁₄O₆P₂
• Pureza: Min. 95%