TBK1/IKKµ-IN-2
CAS: 1292310-49-6
Ref. 3D-SBC31049
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| 10mg | A consultar | |
| 25mg | A consultar | |
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Información del producto
BMS-345541 is a selective inhibitor of TBK1/IKKµ-IN-2, a protein complex that plays an important role in the inflammatory response. It inhibits the phosphorylation of IκBα and IKKβ (inhibitors of NF-κB), thereby suppressing the activation of NF-κB and its downstream inflammatory cytokines. BMS-345541 has been shown to inhibit proinflammatory cytokine production in vitro and in vivo in animals. The drug interacts with both catalytic subunits of TBK1/IKKµ-IN-2, suggesting that it may be used as a potential therapeutic agent for inflammatory conditions such as rheumatoid arthritis or Crohn's disease.
Propiedades químicas
Consulta técnica sobre: 3D-SBC31049 TBK1/IKKµ-IN-2
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