Dabcyl-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-Edans

CAS: 396716-14-6

Ref. 3D-SFQ-3764-PI

Información del producto

• Nombre: Dabcyl-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-Edans
• Sinónimos: DABCYL-TNF-alpha-EDANS (-4 to +6), human Dabcyl-LAQAVRSSSR-Edans, Adam-17 Substrate Ii, Fluorogenic, Adam-17 Substrate Iii, Fluorogenic, Dabcyl-Tnf-Alpha-Edans (-4 To +6) (Human), Dabcyl-Tumor Necrosis Factor-Alpha-Edans (-4 To +6) (Human), Dabcyl-Laqavrsssr-Edans, Tnf-Alpha Convertase Enzyme Substrate, Fluorogenic, Tnf-Alpha Convertase Enzyme Substrate Ii, Fluorogenic, L-Argininamide, N-[4-[[4-(Dimethylamino)Phenyl]Azo]Benzoyl]-L-Leucyl-L-Alanyl-L-Glutaminyl-L-Alanyl-L-Valyl-L-Arginyl-L-Seryl-L-Seryl-L-Seryl-N-[2-[(5-Sulfo-1-Naphthalenyl)Amino]Ethyl]-

Descripción

TNF-a is shed from cell membranes by TNF-a-FW cleaving enzyme (TACE). Incubation of the TACE substrate with recombinant human TACE gives a specific cleavage to restore the quenched fluorescence. The substrate is widely used to screen inhibitors of TNF-α converting enzyme (TACE, ADAM17 endopeptidase) activity. On application is its use as a TACE FRET Substrate I and it is available as a Trifluoroacetate Salt.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 1,573.81 g/mol
• Fórmula: C₇₀H₁₀₄N₂₂O₁₈S
• Pureza: Min. 95%