Información del producto
Zileuton is a cell-permeable inhibitor of phosphodiesterase 4 (PDE4). PDE4 is an enzyme that breaks down the second messenger cAMP. Ligands of PDE4, such as Zileuton, inhibit the reaction of PDE4 with cAMP, which may lead to the accumulation of cAMP in cells and tissues. The inhibition of PDE4 by Zileuton has been shown to be effective in the treatment of asthma, chronic obstructive pulmonary disease (COPD), and rheumatoid arthritis.
Zileuton also activates protein kinase C and inhibits sodium channels in airway smooth muscle cells. It has been shown to reduce airway hyperresponsiveness and inflammation in animal models.
Propiedades químicas
Consulta técnica sobre: 3D-TEA56921 Zileuton sodium
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