NIM811

CAS: 143205-42-9

Ref. 3D-TFA20542

Información del producto

• Nombre: NIM811
• Sinónimos: Sdz nim 811, 9-(N-Methyl-L-isoleucine)cyclosporin A, Nim 811, Nim811, Sdz nim811, Cyclosporin A, 9-(N-methyl-L-isoleucine)-, 30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-3,21-bis(1-methylethyl)-24-(1-methylpropyl)-6,9,18-tris(2-methylpropyl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone

Descripción

NIM811 is an antimicrobial agent that inhibits the growth of a wide range of bacteria by binding to the bacterial ribosome. NIM811 has been shown to be active against resistant mutants and neuronal death in vitro. NIM811 was also shown to protect against mitochondrial membrane potential collapse and to maintain intracellular ATP levels in vivo human cells. The mechanism of action for NIM811 may be due to its ability to inhibit Toll-like receptor signaling, which can lead to the activation of the immune system. This drug has been shown to have synergistic effects when used in combination therapy with other drugs, such as active antiretroviral therapy.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 1,202.6 g/mol
• Fórmula: C₆₂H₁₁₁N₁₁O₁₂
• Pureza: Min. 95%