CDDO Im

CAS: 443104-02-7

Ref. 3D-TSA10402

Información del producto

• Nombre: CDDO Im
• Sinónimos: CDDO-Im, CDDO-Imidazolide, 1-[2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl]-1H-imidazole

Descripción

CDDO Im is a natural compound that has potent antitumor activity and anti-inflammatory properties. CDDO Im may also be useful in the treatment of inflammatory bowel disease by inhibiting the production of chemokines and inducing apoptosis in colonic epithelial cells. It inhibits the activation of NF-κB, which is a transcription factor that regulates the expression of many genes involved in inflammation, including cytokines and adhesion molecules. CDDO Im also inhibits epidermal growth factor (EGF) signaling and cell proliferation. This compound can also induce apoptosis via reactive oxygen species. CDDO Im has been shown to inhibit the lps-induced inflammatory response by decreasing pro-inflammatory cytokine levels and preventing neutrophil infiltration into the gut mucosa.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 541.72 g/mol
• Fórmula: C₃₄H₄₃N₃O₃
• Pureza: Min. 95%