N-(4-(Diethylaminobenzylidenyl)-N'-(4-hydroxybenzoyl)-hydrazine

CAS: 95167-41-2

Ref. 3D-VDA16741

Información del producto

• Nombre: N-(4-(Diethylaminobenzylidenyl)-N'-(4-hydroxybenzoyl)-hydrazine
• Sinónimos: Benzoic acid, 4-hydroxy-, [[4-(diethylamino)phenyl]methylene]hydrazide (9CI), Benzoic acid, 4-hydroxy-, 2-[(1E)-[4-(diethylamino)phenyl]methylene]hydrazide, N'-{(E)-[4-(Diethylamino)phenyl]methylene}-4-hydroxybenzohydrazide, N'-{(E)-[4-(diethylamino)phenyl]methylidene}-4-hydroxybenzohydrazide

Descripción

N-(4-(Diethylaminobenzylidenyl)-N'-(4-hydroxybenzoyl)-hydrazine (MDL-28170) is a small molecule that inhibits the activity of nuclear factor-κB (NF-κB), which is a transcriptional activator of genes. It has been shown to regulate cell function and regression, as well as markers activated by NF-κB in the mitochondria, endoplasmic reticulum, and nucleus. MDL-28170 inhibits the activation of NF-κB in animal models and induces histologic regression in rats with induced prostate cancer. This agent also displays antiestrogenic effects by inhibiting the expression of estrogen receptors alpha and beta.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 311.38 g/mol
• Fórmula: C₁₈H₂₁N₃O₂
• Pureza: Min. 95%