Dequalinium chloride

CAS: 522-51-0

Ref. 3D-W-105841

Información del producto

• Nombre: Dequalinium chloride
• Sinónimos: 1,1'-Decamethylenebis(4-aminoquinaldinium)dichloride
• Marca: Biosynth

Descripción

Dequalinium chloride is a novel, broad spectrum antimicrobial agent with a mechanism of action that inhibits the mitochondria-dependent respiratory chain. Studies have shown that it inhibits the growth of resistant microorganisms in cell-based experiments and in bacterial infections. Dequalinium chloride also has cytopathic effects on thp-1 cells, which are specific for Mycobacterium tuberculosis. In addition to inhibiting mitochondria-dependent respiration, this compound also increases acetylcholine receptor sensitivity in A549 lung cancer cells. Dequalinium chloride is a quaternary ammonium cation and has been shown to be effective against clinical isolates and inhibitory concentrations of a variety of virus species, including human rhinovirus (HRV) and Coxsackie virus type B4 (CoxB4).

Propiedades químicas

• Peso molecular: 527.57 g/mol
• Fórmula: C₃₀H₄₀Cl₂N₄
• Pureza: Min. 95.0 Area-%