Información del producto
Nombre:Hemin
Sinónimos:
- Hemin chloride Chloro(protoporphyrinato)iron(III) Hematin chloride
Marca:Biosynth
Descripción:Hemin is an iron-containing porphyrin (Fe(III) complex of protoporphyrin IX) and is present in human blood. It plays an important role in immune response by facilitating hemoglobin release, increasing the production of reactive oxygen species (ROS) and promoting bacterial lysis. Hemin is also found in Porphyromonas gingivalis and hemophilus influenza bacteria and it may play a role in their virulence since it serves as an iron source for growing cultures. However, hemin has shown antibacterial properties when it binds to serum albumin and some modified porphyrins, and has been reported to trigger cell death in Porphyromonas gingivalis (an oral pathogen) by reducing the iron uptake. This might affect the levels of free hemin that actively affect the peroxidation of low-density lipoproteins (LDL). To prevent the peroxidation, hemopexin captures these globin-free hemin by binding to it and transporting it to the liver, where it is internalized and degraded.
Aviso:Nuestros productos están destinados únicamente para uso en laboratorio. Para cualquier otro uso, por favor contáctenos.
Propiedades químicas
Peso molecular:651.94 g/mol
Fórmula:C34H32ClFeN4O4
Pureza:98.0 To 100.0 Area-%
Color/Forma:Powder
Consulta técnica sobre: Hemin
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