HMN-154

CAS: 173528-92-2

Ref. 3D-YGA52892

Información del producto

• Nombre: HMN-154
• Sinónimos: (E)-4-(2-(2-(N-(4-Methoxybenzenesulfonyl)amino)phenyl)ethenyl)pyridine, Benzenesulfonamide, 4-methoxy-N-(2-((1E)-2-(4-pyridinyl)ethenyl)phenyl)-, Benzenesulfonamide, 4-methoxy-N-(2-(2-(4-pyridinyl)ethenyl)phenyl)-, (E)-

Descripción

HMN-154 is a potent, selective and orally bioavailable small molecule antagonist of the potassium channel Kv1.2 that blocks the channel in a voltage-dependent manner and inhibits action potentials. HMN-154 was developed as a research tool to study Kv1.2 function in cells and tissues, but has also been used as an inhibitor of human Kv1.2 channels in vitro and in vivo. HMN-154 is also being investigated for its effects on other ion channels such as Kv4.3 and Kv4.1, which are expressed in neurons and may play a role in epilepsy or schizophrenia, respectively.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 366.43 g/mol
• Fórmula: C₂₀H₁₈N₂O₃S
• Pureza: Min. 95%