86-MM0835.12-0025 - methyl-cholate | 1448-36-8

<p>Methyl Cholate</p>

Methyl Cholate (Cholic acid methyl ester) is the methyl form of cholic acid.

<p>Applications A bile acid derivative as anti-inflammatory and antitumor agent.<br>References Yasukawa, K., et al.: Chem. Pharm. Bull, 19, 573 (1996), Yasukawa, K., et al.: J. Pharm. Pharmacol., 52, 119 (2000), Iida, T., et al.: Lipids, 38, 281 (2003),<br></p>

<p>Methyl cholate, is used as a bile acid derivative as anti-inflammatory and antitumor agent. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product </p>

Methyl 4-(3,7,12-trihydroxy-10,13-dimethylperhydrocyclopenta[a]phenanthren-17-yl)pentanoate

Cholic acid methyl ester is a bile acid derivative, which is synthesized from cholic acid, a primary bile acid produced in the liver from cholesterol. This compound is obtained through the esterification process, where the carboxylic acid group of cholic acid is modified into its methyl ester form, resulting in enhanced lipophilic properties compared to its parent compound.

<p>Applications Protected Cholic Acid<br>References Suzuki, T., et al.: J. Pharmacol. Sci., 107, 285 (2008), Yasukawa, K., et al.: J. Pharm. Pharmacol., 61, 1051 (2009), Aher, N., et al.: Bioorg. Med. Chem. Lett., 19, 5411 (2009), Huang, L., et al.: Steroids, 74, 701 (2009),<br></p>