86-MM3772.00-0250 - regadenoson | 313348-27-5
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Regadenoson
CAS:Regadenoson (CVT-3146) is a selective A2A receptor agonist that increases coronary blood flow with a longer half-life than adenosine.Fórmula:C15H18N8O5Pureza:99.57% - 99.81%Forma y color:Off-White SolidPeso molecular:390.35Ref: TM-T2671
2mg47,00€5mg65,00€10mg92,00€25mg173,00€50mg273,00€100mg416,00€500mg935,00€1mL*10mM (DMSO)72,00€Regadenoson
CAS:Producto controladoApplications Regadenoson is a selective and potent A2A adenosine receptor agonist (1). The adenosine A2A receptor is a G-protein-coupled receptor and a key therapeutic target for oncologic, inflammatory, Parkinson's and cardiovascular diseases (2). In rodent studies, it has been shown that co-administration of Regadenoson with Temozolomide (T017775) can increase Temozolomide concentration in the brain (3).
References (1) Gao, Z., et al.: J Pharmacol Exp Ther. 298, 209 (2001) (2) Yuan, G., et al.: Expert Opin Drug Discov. 10, 63 (2015) (3) Jackson, S., et al.: J Neurooncol. 126, 433 (2016)Fórmula:C15H18N8O5Forma y color:Off WhitePeso molecular:390.35
