AC-27067 - triethylamine-hydrochloride-99 | 554-68-7

<p>It finds its application as a protein purification reagent. Triethylamine is used as a competing base for the separation of acidic basic and neutral drugs by reverse-phased high-performance liquid chromatography (HPLC). Triethylamine induces visual disturbances (such as foggy vision) in humans, and </p>

Triethylamine hydrochloride

Triethylamine hydrochloride is a potential drug target and can be used to treat infectious diseases. Triethylamine hydrochloride inhibits the polymerase chain reaction, which is an important analytical technique for the detection of DNA sequences. It also has been shown to have antibacterial activity against Escherichia coli by inhibiting protein synthesis in bacteria. This may be due to its ability to form metal chelates with Fe3+, Cu2+, and Mn2+. Triethylamine hydrochloride has also been shown to inhibit the growth of Shigella flexneri and Mycobacterium tuberculosis by regulating transcription elongation through interaction with the RNA polymerase.

<p>Applications Triethylamine Hydrochloride is a hydrochloride salt of triethyllamine (T775740). Triethylamine is used as a competing base for the separation of acidic basic and neutral drugs by reverse-phased high-performance liquid chromatography (HPLC). Triethylamine induces visual disturbances (such as foggy vision) in humans, and is also used in industry as a quenching agent in the ozonolysis of alkenes (e.g. (E)-2-Pentene [P227315]). Triethylamine is used in the purification of drugs which are pharmacologically or chemically similar through separation in reverse-phase HPLC (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br>References 1. Akesson B. et al.: Int Arch Occup Environ Health. 1986;57(4):297-302. 2. Roos RW. et al.: J Chromatogr. 1986 Dec 24;370(3):403-18.<br></p>