Información del producto
- Ganoderic acid C
- Ganoderic acid H
- Lanost-8-en-26-oic acid, 12-(acetyloxy)-3-hydroxy-7,11,15,23-tetraoxo-, (3β,12β)-
- (3β,12β)-12-(Acetyloxy)-3-hydroxy-7,11,15,23-tetraoxolanost-8-en-26-oic acid
Ganoderic acid H( GA-H )and ganoderic acid A(GA-A ) suppress growth (cell proliferation and colony formation) and invasive behavior (adhesion, migration and invasion) of MDA-MB-231 cells; they mediate their biological effects through the inhibition of transcription factors AP-1 and NF-kappaB, resulting in the down-regulation of expression of Cdk4 and the suppression of secretion of uPA, respectively; furthermore, the activity of ganoderic acids is linked to the hydroxylation in the position 7 and 15 (GA-A) and 3 (GA-H) in their triterpene lanostane structure; so hydroxylated triterpenes from G. lucidum could be promising natural agents for the therapy of invasive breast cancers.
Propiedades químicas
Consulta técnica sobre: BP-BP0620 Ganoderic Acid H
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