Tyk2 (phospho-Tyr1054/1055) rabbit pAb

Ref. EK-ES12474

Información del producto

• Nombre: Tyk2 (phospho-Tyr1054/1055) rabbit pAb
• Sinónimos: Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)

Descripción

tyrosine kinase 2(TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008],

• Marca: ELK Biotechnology